新墨西哥海特•克里克的荒芜沙漠，某个小镇附近一辆油罐车发生爆炸，致使主要交通干道瘫痪。当地治安官安妮·弗林（艾曼纽·瓦吉尔 Emmanuelle Vauger 饰）受命前往调查，却在卡车残骸内发现奇怪生物的肢体碎片。与此同时，小镇上一些动物莫名死亡。原来此前一支考古队曾来此发掘，却无意间释放了沉睡地下近一个世纪的恐怖魔兽。嗜血怪物重见天日，开始连番血腥大屠杀。由于爆炸的油罐车阻挡了道路，小镇居民和安妮等人几乎与世隔绝。 在无人施与援手的情况下，安妮等人想方设法杀死怪物，逃出生天……In the desert area of Hat Creek, cows are found partially devoured and the farmers believe that a wolf is attacking the cattle. The alcoholic Sheriff Annie Flynn is called by the local farmer Rob Horn to witness the remains of an animal to request reimbursement from the government and for an accident with a tank truck that is blocking the road. However, Annie sooner discovers that an ancient alien creature sent to annihilate life on Earth hundreds of years ago was released by the Indian Kale during an archaeological excavation in the desert. The Indian Caya and a group of travelers stranded in the spot without gas together with Annie and Kale try to find a means to destroy the alien and save mankind.
