《开膛街》第二季讲述了开膛手杰克之后，白教堂警官们如何在白教堂维护社会安定，缉拿穷凶极恶的凶手。伦敦的这个区，因为开膛手而永远改变了，每次发生犯罪，人们就会想到是开膛手回来了。如何才能让民众感到安全。被谑称为“来自地狱的警官”们，要绞尽脑汁了。Limehouse detective Maurice Linklater is thrown from a window in a house which belongs to a Chinese and his superior Inspector Shine tells Reid he suspects the Triads. However Susan links courtesan Blush Pang to the house and Reid realizes that it an opium den with Blush Pang and an accomplice importing opium, which they are turning into heroin. Reid suspects that somebody in the Limehouse force is Blush Pang's business partner and sets out to prove it whilst Susan has problems with her landlord.
