故事以美国南北战争结束后的中西部旷野为背景，托马斯·道森（约翰·韦恩 John Wayne 饰）白手起家，在养子马修（蒙哥马利·克利夫特 Montgomery Clift 饰）和帮手格鲁特的协助下，他历时14年的辛苦经营，终于在美国德州的一片大草原上建立起自己的大牧场。因为南方经济萧条，托马斯决定把牧场里超过一万头的牛赶往北方的密苏里州贩卖。他召集人马，充分准备，这群西部牛仔赶着大批牛群，开启了这趟千里之旅。 这趟艰难险阻的旅途让牛仔们越发疲倦，也让牧场主托马斯越发固执严厉，逐渐失去人心。终于，马修带头反抗，其他牛仔们也纷纷跟从。把受伤的托马斯留在原地后，这支大部队向另一个方向出发。这趟跋涉千里的赶牛之旅能否走向成功？Fourteen years after starting his cattle ranch in Texas, Tom Dunston is finally ready to drive his 10,000 head of cattle to market. Back then Dunston, his sidekick Nadine Groot and a teen-aged boy, Matt Garth -who was the only survivor of an Indian attack on a wagon train - started off with only two head of cattle. The nearest market however is in Missouri, a 1000 miles away. Dunston is a hard task master demanding a great deal from the men who have signed up for the drive. Matt is a grown man now and fought in the Civil War. He has his own mind as well and he soon runs up against the stubborn Dunston who won't listen to advice from anyone. Soon, the men on the drive are taking sides and Matt ends up in charge with Dunston vowing to kill him.
